Tavneos (avacopan) is a relatively new drug manufactured by Amgen that’s approved to treat ANCA-associated vasculitis (AAV). This group of rare inflammatory autoimmune diseases can impair blood flow in small and medium blood vessels and potentially damage organs.
While AAV is a dangerous condition that requires medical treatment, Tavneos has been discovered to cause serious problems of its own. On March 31, 2026, the U.S. Food and Drug Administration (FDA) began alerting patients and healthcare professionals about serious and even fatal cases of drug-induced liver injury (DILI) associated with the drug.
If Tavneos seriously injured you or someone you love, you may be eligible for compensation. The experienced nationwide drug injury lawyers at Ferrer Poirot Feller have spent decades helping people harmed by medications they thought were safe, and we can help you, too.
If you developed liver problems after taking Tavneos, contact Ferrer Poirot Feller today for a free case review. Our team can help determine whether your diagnosis, timing, and medical treatment may qualify for a claim.
Table of Contents
- How Does Tavneos Work?
- How Does Tavneos Cause Injuries?
- What Are the Symptoms of a Tavneos-Related Injury?
- How Do I Know if I Have a Case?
- What Has the FDA Said About Tavneos Injuries?
- Who Can Be Held Liable for My Tavneos Injuries?
- What Types of Compensation Can I Receive?
- How Can Ferrer Poirot Feller Help With My Case?
- Contact Our Drug Injury Lawyers Today
How Does Tavneos Work?
Tavneos works by blocking the complement 5a receptor (C5aR). The complement system is part of the body’s immune response, but AAV can make it overactive and trigger inflammation. By blocking C5aR activity, Tavneos is designed to reduce inflammation and help prevent immune system attacks on healthy blood vessels.
How Does Tavneos Cause Injuries?
The FDA has warned that Tavneos may cause serious and potentially fatal liver injuries. Reports reviewed by regulators included cases of DILI, hepatic failure, and a rare condition called Vanishing Bile Duct Syndrome (VBDS), which causes the destruction of bile ducts in the liver.
When the liver is damaged, the body may no longer properly process toxins or regulate important bodily functions. Some patients injured by Tavneos have developed severe complications requiring hospitalization, liver monitoring, or emergency medical treatment.
What Are the Symptoms of a Tavneos-Related Injury?
Thus far, the FDA has identified 76 reported cases of liver injury associated with Tavneos, including eight deaths and seven confirmed VBDS cases, three of which were fatal.
Symptoms of a possible liver injury may include:
- Yellowing of the skin or eyes (jaundice)
- Dark urine
- Severe fatigue
- Nausea or vomiting
- Itching
- Light-colored stools
- Swelling or pain in the abdomen
The FDA is advising patients who take Tavneos to seek immediate medical attention if they develop any of these symptoms.
How Do I Know if I Have a Case?
You may be eligible to file a Tavneos lawsuit if:
- You took Tavneos.
- You suffered a serious liver injury or severe infection after using the drug.
- Your injuries required medical treatment, hospitalization, or caused long-term complications.
Potential injuries associated with Tavneos lawsuits may include:
- Drug-induced liver injury (DILI)
- Hepatic failure
- Vanishing Bile Duct Syndrome (VBDS)
- Other serious liver injuries
- Infections requiring hospitalization
- Fatal infections linked to immune suppression
People who lost a loved one due to Tavneos-related complications may also be eligible to pursue a wrongful death claim against the drug’s manufacturer.
What Has the FDA Said About Tavneos Injuries?
In March 2026, the FDA issued a Drug Safety Communication to warn patients and healthcare providers about serious cases of liver injury associated with Tavneos, including fatal cases and reports of VBDS.
Soon after that, the FDA proposed withdrawing Tavneos from the U.S. market. According to the agency, newly discovered information raised concerns about both the drug’s safety profile and whether the medication had been properly shown to be effective for its approved use.
The FDA also stated that the original approval application for Tavneos allegedly contained “untrue statements of material fact.” Although Amgen has publicly disputed the FDA’s conclusions and is contesting the proposed withdrawal, the agency has continued warning patients and doctors about the risks of severe liver damage linked to the drug.
Who Can Be Held Liable for My Tavneos Injuries?
Drug manufacturers like Amgen have a legal responsibility to properly test their medications, disclose all of their known safety risks to the FDA and the public, and warn doctors and patients about potentially dangerous side effects.
Companies involved in the development, marketing, and sale of Tavneos may potentially be held liable if it’s proven that they:
- Failed to adequately warn about liver injury risks
- Failed to properly monitor post-market safety data
- Misrepresented the drug’s safety or effectiveness
- Placed profits ahead of patient safety
Depending on the circumstances of your case, potentially liable parties for your injuries and damages may include Tavneos’s manufacturer, distributors, or other entities involved in making the drug available to patients.
What Types of Compensation Can I Receive?
If you were harmed after taking Tavneos, you may be eligible to recover compensation for many different types of damages, including:
- Medical expenses
- Future medical treatment
- Lost wages
- Reduced earning capacity
- Pain and suffering
- Emotional distress
- Permanent disability or organ damage
- Wrongful death damages for surviving family members
Every case is different, and the amount of compensation available to you and your loved ones depends on the severity of your injuries and their long-term impact on your life. At Ferrer Poirot Feller, we can evaluate the drug’s impact on you and calculate exactly how much money your family is owed for what you’ve experienced.
How Can Ferrer Poirot Feller Help With My Case?
At Ferrer Poirot Feller, our experienced legal team has been protecting the rights of people harmed by dangerous and defective medications since 1981, and we want to help you, too.
We handle drug injury cases across the country, and we’ll fight to get the full and fair compensation you need for your medical bills, lost wages, and pain and suffering. Plus, you’ll never see a bill from us unless we win your case.
Whether Tavneos or another drug injured you or a loved one, Ferrer Poirot Feller can provide the experienced representation and compassionate support you need and deserve throughout the legal process.
Contact Our Drug Injury Lawyers Today
If you or someone you love suffered liver damage, a severe infection, or other serious complications after taking Tavneos, you don’t have to face the aftermath alone. We know what you’re going through, and we’re here to help.
The drug injury attorneys at Ferrer Poirot Feller are actively investigating potential Tavneos claims and helping injured patients understand their legal options. Contact Ferrer Poirot Feller today for a free, no-obligation case review.
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